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human renal proximal tubular epithelial (hk2) cells  (Procell Inc)

 
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    Procell Inc human renal proximal tubular epithelial (hk2) cells
    Human Renal Proximal Tubular Epithelial (Hk2) Cells, supplied by Procell Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+renal+proximal+tubular+epithelial+(hk2)+cells/hk+2+cells/pm40561830-67-0-10
    Average 90 stars, based on 1 article reviews
    human renal proximal tubular epithelial (hk2) cells - by Bioz Stars, 2026-09
    90/100 stars

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    Article Title: BUB1-deficiency suppresses kidney renal clear cell carcinoma progression via the PI3K/Akt pathway: A bioinformatics-oriented validating study.
    Article Snippet: 214 215 Cell culture procedures 216 Human renal cortical proximal tubular epithelial cells (HK2) and renal cancer cell lines 217 (786-O, A498, Caki-1 and 769p) were purchased from Procell Life Science & 218 Technology Co., Ltd. (Wuhan, China).

    Article Title: Radix Rehmannia Glutinosa inhibits the development of renal fibrosis by regulating miR-122-5p/PKM axis
    Article Snippet: Cell culture and treatment Human renal cortical proximal tubular epithelial cells (HK2; CL-0109, Procell Life Science & Technology Co., Ltd., Wuhan, China) were subcultured in DMEM medium supplemented with 10% fetal bovine serum (Thermo Fisher Scientific, USA) and penicillin streptomycin mixture (Beijing Solaibao Life Science, China) at 37°C and 5% CO 2 .

    Article Title: Ferulic Acid Inhibits Partial Epithelial-Mesenchymal Transition in Renal Tubular Epithelial Cells and Mitigates Renal Interstitial Fibrosis by Regulating the HIF-1α/Twist Signaling Pathway.
    Article Snippet: Human renal cortical proximal tubular epithelial cells (HK2 cells, CL- 0109, Procell, Wuhan, China) were obtained for the study.

    Article Title: P110 Inhibits DRP1/FIS1-Mediated Mitochondrial Fission to Alleviate Uric Acid–Induced Apoptosis in HK-2 Cells
    Article Snippet: Human renal proximal tubular epithelial cells (HK2) were procured from Procell Life Science & Technology Co., Ltd. (Wuhan, Hubei, China; Product No. CL-0109) with accompanying official certificates for STR profiling and mycoplasma-free status.

    Article Title: Annexin A2 (ANXA2) regulates the transcription and alternative splicing of inflammatory genes in renal tubular epithelial cells.
    Article Snippet: Human proximal renal tubular epithelial (HK2) cells were obtained from Procell Life Science & Technology Co., Ltd. (Wuhan, Hubei, China).

    Article Title: Radix Rehmannia Glutinosa inhibits the development of renal fibrosis by regulating miR-122-5p/PKM axis
    Article Snippet: Human renal cortical proximal tubular epithelial cells (HK2; CL-0109, Procell Life Science & Technology Co., Ltd., Wuhan, China) were subcultured in DMEM medium supplemented with 10% fetal bovine serum (Thermo Fisher Scientific, USA) and penicillin streptomycin mixture (Beijing Solaibao Life Science, China) at 37°C and 5% CO 2 .

    Article Title: Melatonin attenuates ischemia-reperfusion-induced acute kidney injury by regulating abnormal autophagy and pyroptosis through SIRT1-mediated p53 deacetylation.
    Article Snippet: Ischemia-reperfusion (IR) injury is the leading cause of acute kidney injury (AKI), leading to deteriorated kidney function and high mortality.. However, there are still no potent medications for IR-induced AKI.. Pyroptosis is a type of inflammatory cell death that plays a significant role in IR-induced AKI, and inhibiting pyroptosis might be a promising therapeutic strategy.

    Cell Culture:

    Article Title: Plasma protein affinity, antioxidant, and anti-lung cancer properties of O-methylated flavonol rhamnazin
    Article Snippet: Medicinal herbs can be used for the development of antioxidant and anticancer platforms.. However, the mechanisms by which the bioactive materials show these properties remain largely unclear.. Also, a detailed understanding of the interaction between small compounds and carrier proteins like albumin can provide useful information about the regulation of their stability and circulation time properties.



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    Knockdown of RBCK1 significantly inhibits ccRCC cell proliferation and migration. A Differential expression analysis of RBCK1 between normal and tumor groups. B–D DSS, PFI, and OS survival curves for low- and high-RBCK1 expression subgroups. E Protein expression levels of RBCK1 in normal and tumor groups based on the CPTAC database. F Protein expression levels of RBCK1 in <t>HK2</t> cells and 786-O cells with quantitative analysis (n = 3). G Protein expression levels of RBCK1 in HK2 cells and 769-P cells with quantitative analysis (n = 3). H, I Colony formation assay and Transwell migration assay in 786-O cells (n = 3). J, K Colony formation assay and Transwell migration assay in 769-P cells (n = 3). L, M CCK-8 assay showing cell viability at different time points in 786-O and 769-P cells (n = 3). Data are presented as mean ± SD; significance: * P < 0.05, ** P < 0.01, *** P < 0.001
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    Knockdown of RBCK1 significantly inhibits ccRCC cell proliferation and migration. A Differential expression analysis of RBCK1 between normal and tumor groups. B–D DSS, PFI, and OS survival curves for low- and high-RBCK1 expression subgroups. E Protein expression levels of RBCK1 in normal and tumor groups based on the CPTAC database. F Protein expression levels of RBCK1 in <t>HK2</t> cells and 786-O cells with quantitative analysis (n = 3). G Protein expression levels of RBCK1 in HK2 cells and 769-P cells with quantitative analysis (n = 3). H, I Colony formation assay and Transwell migration assay in 786-O cells (n = 3). J, K Colony formation assay and Transwell migration assay in 769-P cells (n = 3). L, M CCK-8 assay showing cell viability at different time points in 786-O and 769-P cells (n = 3). Data are presented as mean ± SD; significance: * P < 0.05, ** P < 0.01, *** P < 0.001
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    Knockdown of RBCK1 significantly inhibits ccRCC cell proliferation and migration. A Differential expression analysis of RBCK1 between normal and tumor groups. B–D DSS, PFI, and OS survival curves for low- and high-RBCK1 expression subgroups. E Protein expression levels of RBCK1 in normal and tumor groups based on the CPTAC database. F Protein expression levels of RBCK1 in HK2 cells and 786-O cells with quantitative analysis (n = 3). G Protein expression levels of RBCK1 in HK2 cells and 769-P cells with quantitative analysis (n = 3). H, I Colony formation assay and Transwell migration assay in 786-O cells (n = 3). J, K Colony formation assay and Transwell migration assay in 769-P cells (n = 3). L, M CCK-8 assay showing cell viability at different time points in 786-O and 769-P cells (n = 3). Data are presented as mean ± SD; significance: * P < 0.05, ** P < 0.01, *** P < 0.001

    Journal: Discover Oncology

    Article Title: Comprehensive analysis of PANoptosis-related molecular subtypes and prognostic model development of clear cell renal cell carcinoma

    doi: 10.1007/s12672-026-04561-9

    Figure Lengend Snippet: Knockdown of RBCK1 significantly inhibits ccRCC cell proliferation and migration. A Differential expression analysis of RBCK1 between normal and tumor groups. B–D DSS, PFI, and OS survival curves for low- and high-RBCK1 expression subgroups. E Protein expression levels of RBCK1 in normal and tumor groups based on the CPTAC database. F Protein expression levels of RBCK1 in HK2 cells and 786-O cells with quantitative analysis (n = 3). G Protein expression levels of RBCK1 in HK2 cells and 769-P cells with quantitative analysis (n = 3). H, I Colony formation assay and Transwell migration assay in 786-O cells (n = 3). J, K Colony formation assay and Transwell migration assay in 769-P cells (n = 3). L, M CCK-8 assay showing cell viability at different time points in 786-O and 769-P cells (n = 3). Data are presented as mean ± SD; significance: * P < 0.05, ** P < 0.01, *** P < 0.001

    Article Snippet: Human renal proximal tubular epithelial cells HK2, human ccRCC 786-O cells, and human ccRCC 769-P cells were obtained from the American Type Culture Collection (ATCC, USA).

    Techniques: Knockdown, Migration, Quantitative Proteomics, Expressing, Colony Assay, Transwell Migration Assay, CCK-8 Assay